Objective: The purpose of this study was to investigate the ability of the digital imaging and photoshop software as an aid for shade selection in dentistry versus the commonly used visual and instrumental methods. Materials& Methods: Tooth color was assessed in three different methods Visual, Instrumental (Easyshade, and laboratory spectrophotometer) and digital photography. Twenty extracted anterior teeth were used for the in vitro phase while, twenty natural central incisors of volunteers were used for the in vivo phase. Results: For both in vitro and in vivo phases of this study Visual color assessment showed better results than Easyshade and digital imaging respectively. However digital imaging accuracy as a tool for shade selection in dentistry needed more strict conditions to attain more reliable outcome.