Differentiated thyroid cancer (DTC) is a rare disease, especially in children. In childhood, the thyroid gland exhibits higher susceptibility to the carcinogenetic effect of ionizing radiation than in adulthood. Papillary thyroid cancer (PTC) is more prevalent in children. Cancer disease presents at a more advanced stage: 1) primary tumor size at diagnosis is larger 2) neck lymph node involvement 3) distant metastases. The lungs are almost the sole distant metastatic site in children. Additionally, recurrence rates tend to be higher in children; nevertheless, cause-specific cancer mortality remains low.