Aim: To correlate between visual field (VF) sensitivity and retinal nerve fiber layer (RNFL) thickness, as measured by spectral domain OCT in primary open angle glaucoma patients.Methods: Cross-sectional study including 32 eyes of 18 POAG patients, controlled under medical treatment. We correlated mean RNFL thickness measured by OCT with visual field global indices (MD, MS, LV). Also, correlation was done between DDLS, mean RNFL thickness and visual field global indices (MD, MS, LV).Results: The correlation of RNFL and the VF parameters was not significant. Correlation was significant between DDLS & mean RNFL thickness, while it was week between DDLS, MD, MS & LV.Conclusions: Glaucoma is a disease that requires a clinical diagnosis.The correlation between detectable structural and functional damage and change in early glaucoma is at best modest. It is important to include both structural and functional examinations for assessment of glaucoma at each stage of the disease.