The thoracolumbar region consider important area which occursseveral type fractures by trauma or pathological condition specialmetastatic tumors.Thus, fractures of the vertebrae classified into two groupstraumatic and pathological.In our study, all patients present by pain range from mild backpain to severe back pain and if the fracture compressed the spinal cordcause numbness, tingling and weakness of lower extremities.All patients investigated by routine x-ray, CT, MRI and someneed further investigation such case of osteoporosis need measuringbone density by DEXA.Management of patients must be consider individuallyaccording to underlying cause.Our study included 50 patients admitted at Agouza Hospital, 20of them traumatic cause (60%), 20 patients were due to pathologicalcause (40%).Pathway of management include conservative, vertebroplastyand surgical.