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Genetic polymorphisms of caspase 8 and 10genes and risk of non-Hodgkin’s lymphoma

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Clinical & Chemical pathology

Advisors

Arnaoutt, Hanaa H. , Khourshid, Aula M. , Khourshid, Mirvat M.

Authors

Saleh, Muna Hazem El-Nagdi

Accessioned

2017-07-12 06:40:25

Available

2017-07-12 06:40:25

type

M.Sc. Thesis

Abstract

The current study aimed at defining the role of caspase 8 D302H,Caspase 8 652 6N ins/del and caspase 10 I522L genetic polymorphisms as risk factors for NHL. The present study included 100 patients and 100 controls.Genotyping for the genes was done by PCR- RFLP technique. The studyrevealed that CASP8 D302H mutant genotype conferred increased risk for NHLeither alone or with mutant genotypes of CASP8 652 6N ins/del and CASP10I522L. CASP8 652 6N ins/del and CASP 10 I522L gene polymorphisms did notconfer increased risk of NHL.

Issued

1 Jan 2012

DOI

http://dx.doi.org/10.21473/iknito-space/35423

Details

Type

Thesis

Created At

05 Feb 2023