The aim of this study was to evaluate phototherapy with reflectors versus conventional phototherapy; it was a prospective randomized controlled study on 60 full term neonates with non-hemolytic jaundice at EL-Nasr general hospital, Port-said from June 2010 till June 2011. They were divided in two groups, group A (30 neonates) who received phototherapy with reflectors and group B (30 neonates) who received conventional phototherapy they were compared as regard total bilirubin and duration of hospital stay. There was significant decrease in total bilirubin after initiation of treatment then at 12 hr and during till the end of treatment also there was reduction in duration of hospital stay in group (A) than group (B), We Concluded that phototherapy with reflectors is better control in treatment of Neonatal hyperbilirubenemia than conventional phototherapy.