Microcephaly is a common abnormality ; both as an isolafeol anomaly and as acompoenenf of genefie syndromes. The acholoyy of microuphaly is comple. Recurrence risic of 19% affer a single affecred proband las been reporfed.Genetic cases may be a parf of clysmorphic syndnmes. Aclurati diagnosrs is imporfanf for genefic counselling and pnnafal diagnosis.Our microuphalic pafcenls were subjahd to chrmosomal stucly and nearo-radiological evaluation 25% hacl chromosomal abnormalies.