Pre-eclampsia is a pregnancy specific syndrome of reduced organ perfusion secondary to vasospasm and endothelial pathophysiology. This condition is a leading cause of maternal mortality and is responsible for considerable perinatal morbidity and mortality.Also IUGR may be defined as a pathological decrease in the rate of fetal growth. This ultimately results in a fetus who does not achieve its inherent growth potenital, putting him at risk for increased perinatal morbidity and mortality.