This study investigates serum ferritin and insulin resistance in type 2 diabetic Egyptian patients and the relation between both.Sixty subjects were selected: 40 patients with type 2 diabetes mellitus and 20 controls.The results showed significantly higher level of serum ferritin, serum insulin, HbA1c and insulin resistance in type 2 diabetic patients compared with controls.Also a significant positive correlation between ferritin and each of fasting plasma glucose, HbA1c, serum insulin and insulin resistance in patient group.