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Diagnostic usefulness of the random urine Na/K ratio in predicting therapeutic response for diuretics in cirrhotic patients with ascites

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Internal Medicine

Advisors

Hegazi, Muhammad E., El-Shehabi, Amal R., El-Mazni, Ahmad N.

Authors

Emam, Ahmad Mamdouh

Accessioned

2017-07-12 06:42:45

Available

2017-07-12 06:42:45

type

M.Sc. Thesis

Abstract

Twenty-four hour urinary sodium excretion (24-h UNa) of greater than 78 mmol/day is important in the management of cirrhotic ascites. Although the random urine sodium-to-potassium ratio (UNa/K) is strongly correlated with 24-h UNa, and approximately 95% of patients with a random UNa/K greater than 1 have 24-h UNa greater than 78 mmol. To detect the best cutoff point for UNa/K ratio. The study was carried on 60 patients with liver cirrhosis and ascites treated with diuretic therapy. Patients were divided into two groups according to 24-h UNa. We measured spot urine Na/K ratio and 24-h UNa. ROC curve was used to identify the best cutoff point for Na/K ratio. The study showed that UNa/K ratio using cut value of 3, may be an easier and more rapid alternative for the ordinary 24-h UNa collection in cirrhotic patients with ascites. Any time UNa/K ratio using cut value of 3may be an easier and more rapid altenative for the ordinary 24-h UNa collection in cirrhotic patients with ascites.

Issued

1 Jan 2013

DOI

http://dx.doi.org/10.21473/iknito-space/38346

Details

Type

Thesis

Created At

05 Feb 2023