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35495

CT mapping of sentinel lymph node in malignant breast mass: (pilot study)

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

General surgery

Advisors

El-Basyouni, Fahim Aly, El-Shaikh, Essam Aly, Amer, Hesham M. Salah-El-Din

Authors

Amer, Wael Hasan

Accessioned

2017-03-30 06:22:13

Available

2017-03-30 06:22:13

type

M.Sc. Thesis

Abstract

PURPOSE;To evaluate sentinel lymph node mapping in patients with early breast cancer. MATERIALS AND METHODS: Twenty female patients with early breast cancer scheduled to undergo axillary nodal dissection ,as a step of breast conserving surgery or modified radical mastestomy,underwent CT breast and axilla after intralesional lipidol injection by 24 hrs for identification of sentinel lymph nodes . All studied cases were in early stage(T1,T2&N0,N1) without any prior surgical intervention in the same breast nor neoadjuvant chemotherapy .Sentinel nodes were identifiable by enhacement by the lipidol showed on CT films. Results were analyzed statistically. RESULTS: A sentinel lymph node was identified in 6 patients (30%). Lymph nodes were positive for metastatic pathologically in 4 patients (66.7% of those get positive by CT). There were no false-negative findings in this study .100% sensitivity, 87.5% specificity,66.7% positive predictive value, 100% negative predictive value.CONCLUSION:Non enhanced Sentinel lymph node mapping by this technique is appropriate method as a prognostic index for axillary status in patients with early breast cancer who have not undergone prior intervention,nor neoadjuvant chemo and/or radiotherapy .Further study is necessary to ascertain the accuracy of the procedure.

Issued

1 Jan 2003

Details

Type

Thesis

Created At

05 Feb 2023