The study was conducted on 2085 cases of bladder cancer, in Urology and Pathology departments–Faculty of Medicine- Cairo University, between 1990-2002. It has been clearly concluded that, there is an actual change in the pattern of incidence in various histo-pathologic types of bladder cancer in Egypt during the last decade, where squamous cell carcinoma is decreasing, while transitional cell type is strikingly rising. The frequency of bilharzial eggs is on decline. The mean age is rising, and bladder cancer tends to be of higher grade than before. These results need further investigations.