Despite reductions in mortality in cases of pancreaticoduodenectomy, leakage from pancreatic remnant still may cause significant morbidity. Saeveral techniques have been advocated for management of the pancreatic stump after pancreaticoduodenectomy in an attempt to decrease the incidence of postoperative pancreatic fistula and its associated morbidity. No single method has proven to be satisfactory for all patients. In this study, the technique of pancreaticoduodenectomy was retrospectively reviewed as well as different ways of dealing with pancreatic stump in order to compare between them as regard safety and reliability.