Khattab, Muhammad T., Husam, Maha, Abdel-Hamid, Alaa
Authors
Haroun, Eiman Atta
Accessioned
2017-03-30 06:22:27
Available
2017-03-30 06:22:27
type
M.Sc. Thesis
Abstract
Diabetes and impaired glucose tolerance re a cause of significant morbidity and mortality.Impaired glucose metabolism is diagnosed at a fasting blood glucose of >110 and < 126mg/dl (IFG) and postprandial blood sugar >140 and <200mg/dl (IGT).Patients with impaired glucose tolerance may develop frank diabetes. We studied whether there was detectable renal duplex ultrasonographic changes in patients with impaired glucose tolerance compared to a control group and if detectable renal vascular changes occur before the development of frank diabetes. We also examined the intima-media complex thickness of the common carotid artery in both groups. A statistically significant increase was found in the systolic velocity and relative index of the interlobar arteries between the two groups. No statistically significant increase was found in the intima- media complex thickness between the two groups. No fundal changes were detected in either patient or control group.From this we concluded that the renal vascular changes could occur in patients with impaired glucose tolerance and this reflects that impaired glucose tolerance can lead to early vascular changes before patients develop frank diabetes. Lack of significant results for the intima-media complex thickness can be explained by the fact that changes do not affect different segments in the vascular tree in a concordant manner.