We evaluated the effect of foldable soft hydrophobic acrylic intraocular lenses with a sharp edge and a rectangular optic design (Acrysof, MA60BM, Alcon Surgical, Texas, Fortworth, USA) on posterior capsular opacification following cataract extraction in the pediatric age group. The study included 34 eyes. The age ranged from 2 to 12 years. They underwent cataract extraction through a corneal tunnel incision, anterior capsulorrhexis, and automated bimanual irrigation aspiration of the lens matter with preservation of the posterior capsule and thorough cortical cleanup. This was followed by bag implantation of the intraocular lens. These patients were followed up for posterior capsular opacification throughout the duration of the study (mean followup time was 10.6 months with a minimum of 6 months). The incidence of posterior capsular opacification in this study was 94.1%. However, that the incidence of visually significant PCO (grade 4, reaching the visual axis) was 38.2%. It also showed a higher incidence of PCO in young children (Group A, 2-6 years) than older children (Group B, 7 to 12 years). The difference between the 2 age groups was statistically significant (p value =0.001). However, this overall incidence of visually significant PCO was lower than previously published data. The data derived from the current study showed that posterior capsular opacification occurs in almost every child (94.1%) undergoing cataract extraction. However, visually significant PCO can be remarkably reduced using modern surgical techniques and improved IOL design. Acrylic IOLs with hydrophobic material and sharp optic edge effect play an important role in retarding significant PCO following pediatric cataract extraction. Based on the data derived from our study, we recommend modern pediatric cataract extraction techniques with preservation of the posterior capsule and implantation of the AcrySof IOL (Acrysof, MA60BM, Alcon Surgical, Texas, Fortworth, USA) in the capsular bag, which significantly helps in the reduction of the incidence of visually significant PCO. The incidence of visually significant PCO was reduced in children from 2 to 12 years in our study (38.2%). However, this reduction was more pronounced in children over 6 years of age, only 6.3% developed visually significant PCO. In younger children, the incidence of visually significant PCO was 66.7%, which was still lower than the incidence reported in some previous studies. Nevertheless, these encouraging results need to be followed by continued observation to confirm the long-term safety and efficacy of this technique