Approximately 30% of female infertility is caused by ovulation disorders which may be due to ovulatory causes, pituitary causes or CNS hypothalamic causes. MRI is now considered the imaging modality of choice for diagnosis and management of hypothalamic pituitary lesions because of its multiplaner capability and good soft tissue contrast enhancement enabling identification of small lesion. MRI should be done for all cases of infertility with clinical and/or laboratory abnormalities indicating hypothalamic-pituitary axis involvement.