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The role of gated myocardial perfusion SPECT in evaluation of myocardial viability in ischemic cardiac patients, compared to echocardiography

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Nuclear Medicine

Advisors

Amin, Amr , Zaher, Ahmad M. , Salama, Sameh A.

Authors

El-Bedwihi, Marwa El-Sayed

Accessioned

2017-07-12 06:40:33

Available

2017-07-12 06:40:33

type

M.D. Thesis

Abstract

201-Tl myocardial single-photon emission computed tomography(SPECT) is recognized to be an excellent tool for identifying viability aftermyocardial infarction, but being expensive and needing a longer time forimaging are among its main limitations. Hence this study was designedto evaluate the effectiveness of low dose dobutamine echocardiographyand Tc-99m myoview gated SPECT in assessment of myocardial viabilityin comparison to 201-Tl. 35 patients (34 males and 1 females) were included in this study toidentify viable myocardium by defining akinetic or dyskinetic segmentsand compare the wall motion of segments in the echocardiography andmyoview with that in the gold standard 201-Tl scan together withcomparison of the perfusion in Myoview with 201-Tl scan. We compared the segments in patients; we had 560 segments in themyoview, 201-Tl SPECT and echocardiography. Low dose dobutamineechocardiography identified 325/560 segments (58%) as viablemyocardium compared to 525/560 (83.3%) by Tc-99m Myoview gatedSPECT while 201-Tl identified 536/560 (85 %) viable segments.Sensitivity, specificity PPV and NPV for low dose dobutamineechocardiography and Tc-99m Myoview gated SPECT were [60.6 %,100%, 100%, 30.8%] and [98%, 100%, 100% and 93.5%] respectively.Tc-99m gated SPECT scan in better than the low dose echocardiographyin assessment of myocardial viability.

Issued

1 Jan 2012

DOI

http://dx.doi.org/10.21473/iknito-space/35583

Details

Type

Thesis

Created At

05 Feb 2023