The surgical management of children with CHD has been advanced significantly in the past decade. Advances in unders tanding of the mechanisms of myocardial injury so, many strategies for myocardial preservation are based on decreasing myocardial metabolic rate by temperature manipulation and arrest of electromechanical activity. Recent studies suggest the effect of Terminal warm blood cardioplegic in decreasing oxidative stress and free radical release with reperfusion. Forty patients undergoing congenital heart surgery disease were randomly divided into 2 groups TWBC and control group and each subdivided into two groups infants and children haemodynamics parameters were measured lactate and arterial blood gases are measured before and after by pass, Also Troponin I. There was a significant less increase in lactate level and Troponin level of in children receiving TWBC than children of control group. There was a significant less increase in lactate level in infants receiving TWBC than infants of control group but a significant high increase in Troponin level in infants in TWBC group than infants in control group. TWBC has protective effects in children and adolescents as it does in adults. But still, there are some precautions in using TWBC in infants.