This study was conducted on 20 patients having nodular hepatocellular carcinoma from 5 to 7 cm in diameter, Patients were randomized into two groups (10 patients each); The mean age of the first group was 47.12 ± 2.98 and the mean age of the second was 48.30 ± 1.70 The liver biochemical profile in our study showed slight changes after the procedure (slight increase in bilirubin and ALT and reduction in albumen in both groups). Regarding the complications of both procedures: fever, ascites, haematemesis and melena were the most common complications encountered in our study