The number of percutaneous coronary interventions (PCI) prior to coronary artery bypass grafting (CABG) increased drastically during the last decade. Patients are referred for CABG with more severe coronary pathology, which may influence postoperative outcome. Outcomes of 50 CABG patients, collected by a Prospective comparative study, were compared. Group A (n = 25, mean age 53.88 years, 4 women) underwent primary CABG and group B (n = 25, mean age 51.36 years , 4 women) had prior PCI before CABG. Total morbidity was significantly higher in the second group than the first group where 5 patients in group A (non stent group) were affected, while 13 patients were affected in group B (stent group). Inotropes were found to be used more with the previous PCI group rather than group A. ICU stay was longer for group B (53.68 ± 31.45 hrs vs 72.56 ± 54.44 hrs). Previous PCI may has a negative impact on the outcome of subsequent CABG regarding morbidity. However there was no difference in the postoperative mortality. Percutaneous Coronary revascularization should be carefully considered against the higher risk it provides for subsequent CABG. The guidelines for intervention should be strictly followed especially in patients with complex coronary lesions who have higher incidence to be referred for CABG. The number of enrolled patients limits the explanatory power of our study. It is plausible to study the long term outcome to complete the results of short term outcome.