Cesarean delivery rates continue to increase worldwide. Infectiouscomplications after cesarean section are an important cause of maternal morbidity and can prolong length of hospital stay. Diagnosis of a wound infection is relatively obvious in the febrile patient if the wound is unusually tender, inflamed, and indurated or if drainage of purulent material is observed on palpation. A systematic review of literature identifying causes of infection after cesarean section, defining improvement system as skinpreparation , system for prescribing and administrating antibiotics. A continuous quality improvement approach to surgical site infection following cesarean section can improve timely administration of prophylaxis and reduce infections. This study addressed several concerns regarding prophylactic use of antibiotics and its cost effectiveness. In patients undergoing cesarean section, the initial dose of prophylactic antibioticshould be administered after the umbilical cord has been clamped. There is some economic evidence that a single dose of antibiotic is as effective as two-and three-dose regimens and since the efficacy is the same, a single dose of single agent of a broad spectrum antibiotic should be offered.