Wake-up test is used to assess the integrity of the spinal motor pathways during spine surgery . The anesthetic management for wake-up test is challenging for the anesthetist as the patient must be awakened at the proper time , be analgesic , moderately sedated and amnesic.Muscle relaxants are particularly important adjuvant to general anaesthesia since they provide muscle relaxation during the operation and reduce the need for inhalational or intravenous anaesthesia allowing rapid recovery from anaesthesia.From this study we can conclude that mivacurium chloride and vecuronium bromide are appropriate muscle relaxants to be used as infusion for operations requiring wake-up test. But we issued that mivacurium chloride is more suitable than vecuronium bromide as it is a noncumulative drug and provides better recovery profile allowing rapid wake-up test to be done when needed.