Background & Objectives: Risk of blood transfusion is increasingly necessitating the application of blood conservation techniques. Though many studies employed some blood conservation methods, yet a multitechnical program including pre-intra- and postoperative methods were not tried except in few studies. We tried to apply a schematic program on the elective CABG patients, including preoperative stimulation of erythropoiesis, intra operative autologous donation, low priming of the pump, retrograde autologous priming, mediastinal shed blood retransfusion, use of anti fibrinolytics. Methodology: forty patients with IHD were prepared for elective CABG surgery, and divided into two groups, (A) 20 patients underwent our Multimodality techniques. (B) 20 patients treated with the routine usual perioperative management. Results: There were no statistical differences between both groups as regards age, sex, and other preoperative data, as this was considered in the candidate selection. In the study group only one patient received homologous blood mainly due to uncontrolled postoperative chest tube drainage, in contrast the control group patients received blood and blood products with no exception and that was mainly due to low Hg level or excess bleeding or both. The post operative study showed that the implication of blood conservation carries no risks, as the study group did not show any complications or drawbacks, in contrast to the control group; which suffered the risks of blood and blood product transfusion. Conclusion: The blood conservation techniques are feasible, applicable, and almost cost free. Thus they should be -routinely- employed in CABG surgery, and applied to other open-heart surgeries.