Vertebral metastasis are frequent, most prevalent in the vertebral bodies. Vertebral osteoporosis usually involves the geriatric age group causing back pain, which may -if severe- affect their ambulation and quality of life. Vertebral collapse is one of the common complications. Percutaneous vertebroplasty is a recently devised technique concerned with treatment of vertebral bodies by the percutaneous intracorporeal injection of acrylic cement.The aim of this study is the evaluation of percutaneous vertebroplasty in treating vertebral metastasis, osteoporotic vertebrae and vertebral haemangiomas. Twenty four patients have participated in this study for whom thirty one vertebroplasties were performed. Eleven patients had vertebral osteoporosis, eight patients had vertebral neoplasias and five had vertebral haemangiomas.There was considerable improvement in the pain grade and patients ambulation postprocedural. Total resolution of pain and considerable analgesia were noted in 45.8% of the cases respectively.Full ambulation was obtained post-procedurally in 87.5% of our patients. Ambulation with cane was obtained in the other 12.5% of our study population We conclude from this study that vertebroplasty provides immediate and long term pain relief and contributes to vertebral stabilization. Patients having vertebral metastasis, osteoporotic vertebrae and vertebral haemangiomas will benefit from percutaneous vertebroplasty. Cement leakage is apparently related to injected cement volume as it is lower in the osteoporotic group than the neoplastic and haemangioma groups which employ more cement volume.However, the neoplastic group with less cement injection has more cement leakage than the haemangioma group. This can be theoretically explained by the destructive nature of the neoplastic group causing cortical breaks and facilitating the cement leakage, versus the benign nature of the haemangioma group in which the cortical containment usually remains intact and hence diminishes the possibility of cement leakage.