Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted byL cells of the small intestine in response to nutrient ingestionGLP-1 has wide-ranging effects on glucose metabolism, includingstimulation of insulin release, inhibition of glucagon secretion.There is growing evidence that GLP-1 plays an important role in thecardiovascular system such as modulation of heart rate, blood pressure,vascular tone and myocardial contractility