Cystic fibrosis is a genetic disease with multisystem affection of the lungs and pancreas leading to chronic lung disease and malabsorption, which affects the growth of patients. However by early diagnosis through neonatal screening, we can do better control before appearance of complications. Treatment of cystic fibrosis includes proper control of infection, inflammation, mucus clearance of the airways and physiotherapy. In addition to the new lines of treatment such as gene therapy and drugs that corrects the defect in the CFTR gene. This progress in diagnosis and treatment improved the survival and reduced the suffering of patients.