ROP is a retinal disorder of low birth weight premature infants This retrospective study included 100 neonates who were admitted and discharged throughout the period of study (1 year) from El Shohada charity neonatal unit. We aimed to detect ocular abnormalities that could be related to neonatal clinical status and/or management. The results of this ophthalmic screening showed that 10 babies had variable stages of ROP (10%). Significant risk factors for ROP were: birth weight, gestational age, duration of oxygen therapy, and respiratory disorders. We conclude that routine ophthalmic screening of prematures at a predetermined schedule is of utmost importance during and post hospitalization.