Aim of the work was to evaluate the impact of renal transplantation on maternal and fetal morbidity during pregnancy and to comment on the use of immunosuppressive drugs. Patient and method: the study comprises 40 patients divided into two groups as twenty cases who undergone renal transplantation and got pregnant as a study group ; another twenty cases of normal pregnancy as a control group. Conclusion: pregnancy did not reduce renal graft survival, but newborns are at risk of premature birth and low birth weight