Work-related injuries and their disabling outcome remain a pressing worldwide health issue. Thorough knowledge of the trends of workplace disabilities is essential for development of strategies to better assessment and fair judgment. This study examines the circumstances, nature of the occupational injuries and disability among workers presented to the Forensic Medicine Authority in Cairo, Ministry of Justice during two years (2008 and 2009). The information used in this study obtained from reports written by Medico Legal Experts. There were a total of 142 cases of workplace disabilities in different establishments. The mean age was 31.8 years (SD=11.7). Most cases lie between 18 and 34 years of age. There were 10 adolescents below 18 years and 4 elderly above 60 years of age among the sample. Limitation of joint movements was the most frequent type of injury (49.3%), followed by Fractures and Nerve, tendon or muscle injuries (26.8%) each and then came amputation (21.8%). Caught by machine was the most frequent event (40%), followed by falls/slips (20%) then hit by object (13.4%). Hands were the most affected part of the body (28.2%) followed by the back (14.1%) then lower limbs (13.4%).After assessment by MLE, the highest number of workplace disabilities fell in the (0-20%) range presented in 86 victims (60.6%).Disabilities due to falls/slips and being hit by object scored the highest rating percentages, while sitting or standing for long periods scored the least.