Vasculitis defined as a non infections inflammatory disorder of blood vessels, can affect vessels of any type in any organ. The gastrointestinal tract may thus also be involved. The most widely used classification is that according to the size of blood vessels. Vasculitides can cause local or diffuse pathologic changes in the gastrointestinal tract resulting in non specific paralytic ileus, mesenteric ischemia, submucosal edema and hemorrhage, or bowel perforation or stricture. The extent and clinical course of disease depends on the size and location of the affected vessel and histologic characteristics of the lesion. Vasculitis may be primary or can be a manifestation of infection, an adverse drug reaction, malignancy or a connective tissue disease. The diagnosis of gastrointestinal vasculitis is often difficult as the patient symptoms may mimic the symptoms of other diseases.