Two smears were done from the ejaculate of (40) patients with NOA, one was stained with MGG and the other with PSA. PSA identified spermatids in 23/40 (57.5%), while MGG illustrated spermatids in 8(20%). On correlating the results of both stains, MGG identified spermatids in 7/23 (30.4%). PSA has an affinity for terminal mannose residues which is present in the acrosomic vesicles of the spermatids and in any other cell. PSA may give false positive results, while MGG results correlate more with the clinical parameters and histopathology of the patients. We recommend another study, involving a larger group of patients together with performing TESE so as to correlate the results of PSA with TESE outcome.