This is a retrospective stydy including all cases of colon cancer attended at NEMROCK during the period from January 1994, to December 1999. Colon cancer cases represented 1.74% of total malignant cases recorded at NEMROCK during this period. Following modified Astlere-Coller staging system (11.5%) were B2, (38.9%) were B3, (25%) were C2, and (24.6%) were C3. Out of 135 patients (54.1%) received 5-fluorouracil plus leucovorin,and (42.6%) received 5-fluorouracil plus levamisole. At a median follow up period of 40 months ,actuarial 5-year survival for the whole study group was (65.5%),and 5-year disease free survival was (56.7%).