Dyspepsia refers to pain or discomfort, which is centered in the upper abdomen. Discomfort refers to subjective negative feeling that the patient does not interpret as pain, with or without symptoms of early satiety, bloating, nausea or vomiting. Regarding the pathogenesis of functional dyspepsia, there are a number of different mechanisms that have been proposed to explain it, as mucosal inflammation and H. pylori infection, gastric acid, disturbed motor function, disturbed sensory function, central nervous system disturbance, diet and environmental factors. H2-receptor blockers and proton-pump inhibitors are the most widely used drugs for treatment of functional dyspepsia. Again, many studies showed the outcome to be unpredictable and conflicting (Talley, 2000). The results of the present work showed no age prevalence of functional dyspepsia but there was prevalence of female sex 62%(31/50) among patients with functional dyspepsia, most of the patients were housewives 44%(22/50). Fifty six percent of patients (28/50) were from urban areas.There is significant improvement of most of the patients symptoms to each regimen of drugs included in the study. However there is no significant privilage in the response of functional dyspepsia to five regimens of drugs included in the study.