Background: Dilated cardiomyopathy (DCM) is characterized by impaired systolic function of one or both ventricles. The aim of this study to assess left ventricular (LV) function in DCM patients using tissue Doppler imaging.Methods: We studied 30 patients with DCM (4.4± 3.3 years) and 10 controls (6.7 ± 4.9 years). Mitral annular S' and E' velocities were recorded. LV systolic, diastolic and time to peak systolic velocities were recorded at lateral and septal walls. Results: S' was correlated with E' at the mitral annulus, there was a significant positive correlation between mitral S´ and E´ waves in cases (r = 0.6, p = 0.000) and controls (r = 0.7, p = 0.01).Cases had a significant difference of S', E' and A' waves between the different segments of LV (p < 0.05) and no difference of TP between the different segments of LV (p = 0.341).Conclusion: In pediatric DCM, systolic and diastolic functions are related. There is regional heterogeneity of systolic and diastolic functions of LV. No left ventricular systolic dyssynchrony.