This study is to evaluate the role of triphasic CT in prediction of the prognosis of the irresectable HCC patients who had locally treated with transcatheter arterial chemo embolization by studying the enhancement (vascularity) pattern and the volume changes of the HCC after TACE.Our study included 25 HCC patients as diagnosed by triphasic CT study and serum AFP level. Patients were recruited from NHTMRI HCC clinic and radiology department for assessment of the target lesion after doing TACE as a loco regional therapy for HCC from September 2012 to July 2013.In our study, there is a highly significant relationship between the maximum initial diameter of the target lesion before TACE and the maximum diameter of the lesion after TACE as the initial maximum diameter of the target lesion is increased the maximum diameter of the lesion after TACE is also increased.