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3 Biochemical markers in blood can predict cirrhotic evolution of chronic hepatitis

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Clinical & Chemical Pathology

Advisors

Khalil, Muna S. , El-Abd, Nivin E. , Muhey-El-Din, Abir M.

Authors

Mahmoud, Wael Muhammad Nabil

Accessioned

2017-04-26 12:34:25

Available

2017-04-26 12:34:25

type

M.Sc. Thesis

Abstract

In this study, it was found that there was significant difference in median fibronectin, pseudochoinesterase, prothrombin and equation levels with the degree of fibrosis, P<0.05. Also, when ROC, curve was poltted; it was found that the equation significantly was discriminate between fibrosis and cirrhosis at cut off value of 243.28{AUC= 0.802, SENSIVITY WAS 100% AND SPECIFICITY WAS 60%}. In our study, there was significant positive correlation between fibronectin and other parameters (pseudocholinestrase, prothrombin activity, ALP and albumin) (p < 0.05 each). Also, there was significant negative correlation between the equation and the degree of fibrosis; r= -0.642, p<0.

Issued

1 Jan 2009

DOI

http://dx.doi.org/10.21473/iknito-space/33208

Details

Type

Thesis

Created At

31 Jan 2023