AKI is a serious complication post CABG. The off-pump technique was developed to avoid the post operative complications of the pump. Our aim is to assess the incidence of AKI in both and the impact of plasma and urinary NGAL in predicting AKI . 45 patients undergoing CABG were studied ; 25 by the off pump technique and 20 by the on pump. Plasma and urinary NGAL were measured 2 hours post operative (by ELISA). 15 patients ( 33.3%) had AKI ,11 ( 73%) were classified as Stage I and 4 ( 27%) as stage II ( AKIN ) AKI occurred in 10 patients (40 %) of the 25 patients who underwent off-pump procedure and 5 ( 33.3% ) of the 15 (on pump) (P>0.05). The sensitivity and specificity of plasma NGAL were 80 %, 70% respectively, while those of urinary NGAL 93%, 66%, respectively. AKI wasdeveloped in 33.3 % of cases who underwent CABG , the incidence was not different between both procedures. Urinary NGAL was more sensitive than plasma NGAL in predicting AKI and is a more positive than negative test