Aim of the study: The purpose of the present study was to assess the prevalence of FSD among diabetic women and the possible risk factors. Patients and methods: Five-hundred married women were interviewed to answer Female Sexual Function Index (FSFI) questionnaire. The women were classified into two groups. The first group included 400 diabetic patients (diabetic group), while the second (control group) included 100 non-diabetic women. Parameters of patients' evaluation included the following: history, FSFI questionnaire, urine analysis for albumin, and blood glucose testing. Results: There was a statistically significant decreased desire, and arousal domains in diabetic patients compared to control candidates. Although the prevalence of Female Sexual Dysfunction (FSD) was greater in the diabetic group than the control one, this was statistically non-significant. Conclusion: FSD affects diabetics more often than non-diabetic women. Coronary artery disease, hypertension, and peripheral neuropathy were associated with a significant increase in FSD. On the other hand, age, obesity, educational level, type and duration of diabetes, glycemic control, and nephropathy had no significant effect on FSD.