Purpose: To evaluate the postoperative visual efficacy, and complication rate after intraocular implantation of an iris-claw aphakic intraocular lens (IOL).Setting: Research Institute of Ophthalmology and Abo El Reesh children hospital, Cairo University.Design: Case series.Methods: This chart review comprised 25eyes with no capsule support that had anterior iris-fixation IOL implantation for aphakia between 2011 and 2012.Results: The study comprised 25 eyes (18 patients). Iris-claw IOLs were inserted during primary lens surgery in 18 eyes and as a secondary procedure in 7 eyes. The mean post operative best corrected visual acuity (BCVA) was (0.51 ± 0.19).There was a highly significant increase in BCVA in comparison with the pre operative value (0.17 ± 0.11) .There was a highly significant decrease in endothelial cell count (ECC) 1 month post operative (3081.64 ± 495.3) in comparison with the pre operative ECC (3573.36 ± 468.9). There was a non significant decrease in cell count 1 year post operative (2894.24 ± 444.6) in comparison with cell count 1 month post operative (3081.64 ± 495.3). Conclusions: Iris-claw IOL implantation for aphakia gave a good visual outcome and can be used for a wide range of indications. Postoperative complication rates were better than, those with conventional anterior chamber IOLs and sulcus scleral fixation IOLs.