The soluble transferrin receptors are one of the most important markers in iron deficiency anaemia. It is related to the intact receptors concentration. This study was undertaken to evaluate immunoturbidimetric “I.T”, immunonephelometric “I.N” and ELISA methods for estimation of sTfR. In precesion study, the I.T method showed an excellent C.V of 4.46% & 3.4% respectively. As for I.N method it was 4.3% for the high control, and unacceptably high high for the low control. 18%. For the ELISA method, it was acceptable “10% & 5%”. The LDL was acceptable for both I.T “0.07mg/l” & ELISA methods “47.6u/l”.