37062

The relationship between sleep and epilepsy and their impact on the quality of life and cognitive functions

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Neurology

Advisors

Aulwan, Hasan , El-Tamawi, Muhammad S. , Salem, Seyam S.

Authors

Gaber, Muna Muhammad

Accessioned

2017-03-30 06:21:18

Available

2017-03-30 06:21:18

type

M.D. Thesis

Abstract

Sleep disturbances are well-documented associations in epileptic patients even before AEDs treatment, and even in non-symptomatic epilepsy. TLE group had more sleep abnormalities compared to generalized group. NREM sleep has a facilitating effect on IID especially lighter stages (stage I and II), while REM has anti-epileptogenic effect. Chronic carbamazepine and valproate monotherapy have restorative and normalizing effects on sleep pattern especially when used as monotherapy in idiopathic epilepsies, they improve subjective daytime sleepiness. Cognitive deficits are observed in epileptic patients with normal IQ, and in recently diagnosed epileptics. Untreated epileptic patients had significant excessive daytime sleepiness compared to controls. Seizure frequency still the key factor influencing patient’s perception social dysfunction

Issued

1 Jan 2005

Details

Type

Thesis

Created At

31 Jan 2023