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Predicting successful outcomes in living-donor liver transplants

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Internal Medicine

Advisors

El-Garem, Nuaman M. , El-Amir, Muna M. , Helmi, Ayman S. , Rezq, Amal R.

Authors

El-Mesiri, Rim Medhat Abdel-Munaem

Accessioned

2017-07-12 06:40:59

Available

2017-07-12 06:40:59

type

M.D. Thesis

Abstract

This study was conducted on twenty Living donor liver transplantation (LDLT) recipients from Liver Transplantation unit in Kasr El Eini hospital. All patients were transplanted for end-stage liver disease (ESLD) and hepatitis C virus (HCV). Patients with hepatocellular carcinoma (HCC) were excluded. The aim of this work was to study the value of procalcitonin (PCT) as well as hepato-biliary iminodiacetic acid scan (HIDA scan) as markers for survival following Liver Transplantation (LT). PCT was measured one day preoperatively as well as one day, four days and eight days postoperatively and PCT levels were correlated with sepsis. HIDA scan was performed three weeks and three months following LT. HIDA scan results were compared with abdominal ultrasound (US) findings and laboratory tests to assess the graft function. PCT was found to be a powerful prognostic factor in detecting mortality due to sepsis following LDLT. HIDA scans were found to be noninvasive, reliable modality for assessing graft function and early diagnosis of post-transplantation biliary complications. However, correlation with clinical status and imaging modalities is essential to confirm detected abnormalities.

Issued

1 Jan 2014

DOI

http://dx.doi.org/10.21473/iknito-space/36099

Details

Type

Thesis

Created At

31 Jan 2023