Osteoporosis is one of the most common bone diseases seen in clinical practice, Risk factors for osteoporosis have several important roles to play in the investigation, prevention, and treatment of osteoporosis. The aim of this work is to study clinical risk factors for type-I osteoporosis among postmenopausal Egyptian women. Seventy five postmenopausal women were included in the present work, they were divided into: Group-I: 50 postmenopausal osteoporotic women and Group-II: which included twenty five women with normal bone densitometry. Information was collected via a standardized questionnaire. All subjects were subjected to: Full history taking, complete examination, measurement of weight, height and body-mass index. The results of this study revealed that: there was reduction in menopause age (early menopause) of group-I with a highly significant statistical difference. Late menarche appeared to be a risk factor for osteoporosis with a very high significant statistical difference (P<0.00001), as well as low body weight and low body mass index, Also the results showed that hysterectomy was a risk factor for osteoporosis in this study. High dietary calcium intake, high consumption of milk, calcium and vitamin D supplementation, physical activity, regular walking and postmenopausal HRT were a protective factors for osteoporosis. It can be finally concluded that: Women with multiple risk factors and lower bone density have an especially high risk of osteoporosis. Maintaining body weight, BMI and walking for exercise are among the steps that may decrease the risk. Calcium and vitamin D supplementations are recommended around the age of 25 years especially during pregnancy and lactation periods.