Combined cardiac and hepatic disorders occur in three different settings : heart diseases affecting the liver, liver diseases affecting the heart, cardiac and hepatic disorders with joint etiology. Modifications of cardiac function in cirrhotic patient with or without ascites refer as abnormalities in cardiac functions have been reported in liver cirrhosis suggesting a latent cardiomyopathy in these patients. Diminished myocardial beta adrenergic receptor function has been shown to play an important role in pathogenesis of cirrhotic cardiomyopathy. In addition to abnormalities in circulating humoral factors such as catecholamines Nitric oxide, carbon monoxide. Liver cirrhosis is associated with various circulatory abnormalities as enlarged cardiac chambers, diastolic disfunction, pulmonary hypertension are more evident in cirrhotic patients with ascites. Nitric oxide plays a significant role in ciculatory abnormalities and haemodynamic changes occurs in liver cirrhosis and pathogenesis of cirrhotic cardiomypathy. Serum level of nitric oxide increased in liver cirrhosis (regardless ascites). The more deterioration of liver function in liver cirrhosis and presence of ascites; the more increasing of cardiac abnormalities and serum level of Nitric oxide.