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Microalbuminuria in type 1 diabetics : Risk factors, progression and prevention

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Pediatrics

Advisors

Metwalli, Nermin S. , Hasan, Fayza A. , Hasan, Muna M.

Authors

Abdel-Hamid, Abdel-Hamid Ezzat

Accessioned

2017-03-30 06:20:57

Available

2017-03-30 06:20:57

type

M.Sc. Thesis

Abstract

The aim of the present study was to find out the annual and cumulative prevalence of microalbuminuria (MA) in type 1 diabetics attending the Diabetic Endocrine Metabolic Pediatric Unit (DEMPU) identifying its course, risk factors and its relation to glomerular filtration rate.Methods : We studied 90 children and adolescent (49 females and 41 males) with type 1 diabetes mean ages 15.6 4.4 yrs, mean duration of DM 8.6 4 yrs. Creatinine clearance, albumin excretion rate (AER), were tested.Results and Conclusion : The annual prevalence of albuminiuria at DEMPU is 13.5% and the cumulative prevalence is 35.5%. The majority (86) were pubertal only 4 were prepubertal with diabetes duration less than 5 years. It seems that not all diabetics with sub-optimal glycemic control and poor compliance are at risk of developing microalbuminuria. Family history of cardiovascular diseases (CVD) appears to be a significant indicator of those at risk and raised blood pressure is found in association with development and progression of microalbuminuria. Creatinine clearance can be an indicator of progress and persistence of MA.

Issued

1 Jan 2004

Details

Type

Thesis

Created At

31 Jan 2023