Once a contact lens is removed from its storage container, it is liable to pollution which meanscontamination by materials and invasion by microorganisms, that may interfere with eye health, and thequality of vision. A variety of organic, inorganic and mixed deposits may adhere to the contact lenssurface leading to its spoilage. These deposits are proteinatious fine crystalline from tear film (Fowler andAllan Smith, 1980),while lipids deposits arise from meibomian glands and other sebaceousglands(Wedler,1987). These deposits impair lens transparency & reduce oxygen transmissibility of thelens leading to corneal pathological changes. The deposits can provide an environment for adhesion andproliferation of microorganisms with possible development of infectious keratitis Pollution withmicroorganisms is one of the most serious hazards of contact lens wear, This risk may be increased byplacing pieces of plastic (contact lenses, shells or drug release devices) in the conjunctival sac, which maynot be sterile and may interfere with the tears, the carriers for many of the eye's defenses against infection(Stapleton et al ., 1993).