Resistin, a 12.5-kDa protein encoded by a region on chromosome19 in humans, is a 108-amino-acid prepeptid (Meier U. et al. 2004). Itincludes a signal peptide, a variable region, and a conserved C-terminus(Steppan CM et al. 2004). Resistin circulates in human blood as adimeric protein consisting of two 92-amino acid polypeptides that arelinked by a disulfide bridge and forms high- and low-molecular weightcomplexes (Koerner A, et al. 2005).This study aimed at demonstrating the relationship of resistin levelwith estimated eGFR, the most established marker of kidney impairmentin hypertensive subject and the relationship of resistin level with albuminto creatinine ratio as marker an established index of diffuse vasculardamage, in hypertensives