Heavy metals are among the most wide spread potential chemical contaminants in the environment. Cadmium, mercury, and lead are those which are most dangerous to human health.Chronic lead toxicity is one of the most dangerous pollution problems in Egypt, and children are the most affected group. A relation between blood lead level and ascorbic acid administration is under demonstration, if the effect of ascorbic acid in lowering the blood lead level is demonstrated, it will be beneficial to face this problem by an easy and cheap method.Blood and urine lead levels were estimated among a group of children then Ascorbic acid was administered orally in a total dose of 1000 mg/day in four divided doses for a week then blood and urine lead levels have been estimated we have found that the level of lead has decreased in blood and urine this show that ascorbic acid has a role in decreasing blood lead level and it can be used for prevention and treatment of lead toxicity.