This study investigated the accuracy of ultrasonography and duplex-Doppler in predicting the final diagnosis in 80 patients with compensated HCV related chronic liver disease in comparison to histopathological diagnosis which revealed. A highly significant positive correlation between liver surface and fibrosis stage and a significant negative correlation between portal vein peak velocity and fibrosis stages. There was a highly significant correlation between left lobe span ( in ML) and splenic size with steatosis grades. There was a significant positive correlation between quadrate lobe (TD) and liver texture and presence of HDLN with steatosis grades. There was a significant positive correlation between right lobe span (in MCL) and HAI, also there was a significant negative correlation between HA resistive index and HAI.