Sexual dysfunction in epilepsy appears to be multi factorial. We analyzed sexual functions and hormone blood levels in 90 male subjects (50 epileptics with sexual dysfunction, 20 epileptics without sexual dysfunction and 20 controls). We used the International Inventory of Erectile Function (IIEF) questionnaire to assess the patients’ sexual functions. Assessment of blood levels of prolactin, total testosterone, sex hormone binding globulin, estradiol, dehydroepiandrosterone sulfate, follicle stimulating hormone and luteinizing hormone were preformed.